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Less Stress Over Late Dosages
You don’t have to stress if you forget to administer the dose at the right time, because Advantage Multi keeps working even if applied a few days late. Be sure to apply it immediately and resume the usual dosage schedule to keep your pet protected. Per product label, Advantage Multi for Cats should be applied monthly.

Vet-Prescribed Protection
Multi-layered parasite protection from heartworm disease, fleas & intestinal worms.

Easy to Apply
For ultimate convenience, Advantage Multi packs layers of protection into a single, once-a-month topical solution. No extra steps or hard-to-swallow pills.


How should I apply Advantage Multi to my cat?
After breaking the seal on the tube (see package for instructions), part the hair on the back of your cat’s neck at the base of the head. Place the tip of the tube on the skin and apply the entire contents directly on the exposed skin.

How often should I give Advantage Multi to my cat?
Continuous, monthly treatment is recommended for reliable year-round protection against all five pests. Consult your veterinarian regarding your specific pet’s needs.

How does Advantage Multi protect against fleas?
Advantage Multi is a topical solution that works on the skin to kill through contact, so fleas don’t have to bite your cat to die.
Product Description
Give your cat Advantage Multi for Cats – the monthly topical solution for cats. Advantage Multi for Cats not only prevents heartworm disease, it also treats and controls flea infestations, intestinal worms including roundworms and hookworms, and ear mites – the #1 cause of ear infections in cats.*
Your cat or kitten must be at least nine weeks old and weigh between 5.1 and 9.0 lbs. to use this formula.
Advantage Multi is only available by prescription. Subscribe to regular doorstep deliveries of 3-dose or 6-dose packs so you never miss a monthly treatment. Before starting any heartworm prevention program, it’s important for your veterinarian to test your cat for an existing heartworm infection.
Advantage Multi for Cats is a trädemark of Elanco or its affiliates.
*Yang C, Huang HP. Evidence-based veterinary dermatology: a review of published studies of treatments for Otodectes cynotis (ear mite) infestation in cats. Vet Dermatol. 2016(Aug);27(4):221-e56.
INDICATIONS Advantage Multi for Cats is indicated for the prevention of heartworm disease. Advantage Multi for Cats kills adult fleas and is indicated for the treatment of flea infestations. Advantage Multi for Cats is also indicated for the treatment and control of ear mite infestations and the following intestinal parasites: Hookworm and Roundworm.
Important Safety Information
CAUTION: Federal (U.S.A.) law restricts this drug to use by or on the order of a licensed veterinarian. WARNINGS: Do not use on sick or debilitated cats or ferrets. Do not use on underweight cats. (see ADVERSE REACTIONS). Do not use on cats less than 9 weeks of age and cats or ferrets less than 2 lbs body weight. PRECAUTIONS: Avoid oral ingestion. HUMAN WARNINGS: Children should not come in contact with the application site for 30 minutes following application.
Package Dimensions : 6.25 x 3.13 x 2.4 inches; 1 ounces
Item model number : 28854683PK
Date First Available : March 27, 2025
Manufacturer : Elanco
ASIN : B0F5J1RQFH
Best Sellers Rank: #45,891 in Pet Supplies (See Top 100 in Pet Supplies) #12 in Prescription Cat Medications
Customer Reviews: 4.6 4.6 out of 5 stars (8) var dpAcrHasRegisteredArcLinkClickAction; P.when(‘A’, ‘ready’).execute(function(A) { if (dpAcrHasRegisteredArcLinkClickAction !== true) { dpAcrHasRegisteredArcLinkClickAction = true; A.declarative( ‘acrLink-click-metrics’, ‘click’, { “allowLinkDefault”: true }, function (event) { if (window.ue) { ue.count(“acrLinkClickCount”, (ue.count(“acrLinkClickCount”) || 0) + 1); } } ); } }); P.when(‘A’, ‘cf’).execute(function(A) { A.declarative(‘acrStarsLink-click-metrics’, ‘click’, { “allowLinkDefault” : true }, function(event){ if(window.ue) { ue.count(“acrStarsLinkWithPopoverClickCount”, (ue.count(“acrStarsLinkWithPopoverClickCount”) || 0) + 1); } }); });
Advantage Multi for Cats delivers 5-in-1 protection from fleas, ear mites, intestinal worms & heartworm disease
Veterinarian-trusted formula delivers 30 days of protection in each dose
Kills fleas through contact; pests don’t have to bite your cat to die
Treats ear mite infestations
Easy-to-apply topical treatment, no hard-to-swallow pills
4 reviews for Advantage Multi for Cats 5-in-1 Heartworm Prevention | Kills Fleas & More | Cats 9.1-18 lbs. | 6-Month Supply
Add a review
$129.79
Krystina Madej –
Good
Nice.. No more fleas or ticks
Deb –
great price
just what i ordered, great price arrived quickly.
DandBCannon –
Not only for cats
We use this flea medicine for rabbits. It is very helpful to them. We appreciate the seller going through Amazon, it is very convenient.
glen renfroe –
Dangerous
Killed my cat